PO-01-222 LONG-TERM IMPACT OF ADDITIONAL ABLATION AFTER PULMONARY VEIN ISOLATION: RESULTS FROM EARNEST-PVI TRIAL

An optimal strategy for left atrial ablation in addition to pulmonary vein isolation (PVI) patients with persistent fibrillation (AF) has not been determined. EARNEST-PVI trial previously reported that PVI-plus (PVI followed by additional ablation, including linear or targeting areas complex fractionated electrograms [CFAE]) was possibly superior PVI alone AF patients. To elucidate long-term impact of The present study extended the follow-up period 3 years after enrollment trial. Primary outcomes recurrence rate and/or tachycardia (AT) were compared between PVI-alone group (n=248) and (n=245). In addition, also on-treatment groups categorized actually created lesions. AF/AT lower randomly allocated than (29.0% vs. 37.5%, p=0.036). On-treatment analysis revealed + (n=205) demonstrated a those only (26.3% 37.8%, p=0.007). contrast, CFAE (n=37) had comparable (40.5% p=0.76). At second 126 recurrence, ATs excluding common flutter more frequent (32.6% 5.7%, p<0.0001). Left efficacious during 3-year follow up. Linear other strategies, but may increase iatrogenic ATs.